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郑素清

主要研究抗肿瘤和抗炎药物的设计与合成,同时也设计抗肿瘤药物的高分子递送系统。长期从事《药物化学》、《药物化学实验》和《分析化学》的本科生教学工作。目前主要在journal of medicinal chemistry、Frontiers in Chemistry、Frontiers in Chemistry  等著名杂志发表论文20多篇。
姓名  郑素清 性别  女
职称  副研究员 学位  博士
职务   电子邮件  2629439311@qq.com

专业研究方向:物化学,计算机辅助药物化学,有机合成方法学

教学成果:温州医科大学校级微课比赛三等奖

科研成果:

1.主持、参与科研项目

2016.1.1-2018.12.31具有双重结合位点作用的烯丙基型查尔酮类PTP1B选择性高效抑制剂的设计合成及其药理活性研究国家自然科学基金青年基金 主持

2.发表论文(具有代表性的5篇)

(1)Acid-responsive nanoparticles as a novel oxidative stress-inducing anticancer therapeutic agent for colon cancerChengwei Zhao, Weilan Cao, Hailun Zheng, Zhongxiang Xiao, Jie Hu, Lehe Yang, Min Chen, Guang Liang, Suqing Zheng, Chengguang Zhao.Int J Nanomedicine.2019;14: 1597–1618.

(2)e-Bitter: Bitterant Prediction by the Consensus Voting From the Machine-Learning MethodsSuqing Zheng, Mengying Jiang, Chengwei Zhao, Rui Zhu, Zhicheng Hu, Yong Xu, Fu Lin.Front Chem. 2018; 6: 82

(3)e-Sweet: A Machine-Learning Based Platform for the Prediction of Sweetener and Its Relative Sweetness

Suqing Zheng, Wenping Chang, Wenxin Xu, Yong Xu, Fu LinFront Chem. 2019; 7: 35

(4)Proposed Hydrogen-Bonding Index of Donor or Acceptor Reflecting Its Intrinsic Contribution to Hydrogen-Bonding Strengths. J. Chem. Inf. Model., 2017, 57(7),1535-1547

(5)Osthole Protects against Acute Lung Injury by Suppressing NF-κB-Dependent Inflammation.Yiyi Jin, Jianchang Qian, Xin Ju, Xiaodong Bao, Li Li, Suqing Zheng, Xiong Chen, Zhongxiang Xiao, Xuemei Chen, Weiwei Zhu, Weixin Li, Wencan Wu, Guang LiangMediators Inflamm. 2018; 2018: 4934592.





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